Brian Clyde was born and raised in Manhattan where he attended New York University's Tisch School of the Arts. After graduating in 1999, his senior thesis won Best Short Narrative at the Seattle Underground Film Festival in 2000. This caught the eye of filmmaker Roger Corman who decided to finance Clyde's first feature, Rage and Discipline, which Clyde wrote and directed. Rage and Discipline received a favorable review from Ronnie Scheib of Variety Magazine and an Honorable Mention at the African Diaspora Film Festival.

Clyde went on to direct two more feature films for Corman and is currently finishing a feature-length documentary about small, sustainable farms in the Hudson Valley region of New York State. He is scheduled to direct a fifth feature in December of 2012.